Publications

Selected Publications

Needham, S. R. Binying Ye, J. Richard Smith and William D. Korte. “Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Pyridostigmine Bromide from Guinea Pig Plasma.” Journal of Chromatography B. 796. 347-354. 2003.

Needham, S.R. “Bioanalytical Method Validation: Example, HPLC/MS/MS Bioanalysis of an Anti-Nerve Gas Agent Drug for Homeland Security.” American Pharmaceutical Review Summer Issue 2003.

Needham, S. R. and Tim Wehr. “Fast, Efficient Separations in Drug Discovery: LC/MS Analysis Using Column-Switching and Rapid Gradients.” LC-GC Europe April, 2001.

Needham, S. R. and P. Brown. “The Role of the Column for the Analysis of Drugs and Other Components by HPLC/MS: Part II.” American Pharmaceutical Review Spring Issue 2001.

Needham, S. R. and P. Brown. “The Role of the Column for the Analysis of Drugs and Other Components by HPLC/MS: Part I.” American Pharmaceutical Review Winter Issue 2000.

Needham, S. R.. “Fast, Efficient Separations in Drug Discovery: LC/MS Analysis Using Column-Switching and Rapid Gradients.” LC-GC November, 2000 (editors request).

Needham, S. R., P. Jeanville, P. Brown and E. Estapé. “Performance of a Pentafluorophenylpropyl Stationary Phase for the High Performance Liquid Chromatography/Mass Spectrometry/Mass Spectrometry Assay of Cocaine and its Metabolite, Ecogine Methyl Ester in Human Urine.” Journal of Chromatography B. 748. 77-88. 2000.

Needham, S. R., P. Brown, K. Duff and D. Bell. “Optimized Stationary Phases for the HPLC/ESI/MS Analysis of Basic Pharmaceuticals.” J. of Chromatogr. A. 869. 159-170. 2000.

Needham, S. R., Patrick M. Jeanville, Estela S. Estapé and Mark J. Cole. “Rapid Confirmation/Quantitation of Cocaine and Benzoylecgonine in Urine Utilizing High Performance Liquid Chromatography and Tandem Mass Spectrometry.” Journal of the American Societry for Mass Spectrometry. 11:3:257-263. 2000.